Based on the best-selling book "The Parallel Curriculum", this professional development resource gives multifaceted examples of rigorous learning opportunities for science students in Grades 6-12. The four sample units revolve around genetics, the convergence of science and society, the integration of language arts and biology, and the periodic table. The editors and contributors provide user-friendly methods for creating more thoughtful lessons and show how to differentiate them for the benefit of all students. Included are field-tested and standards-based strategies that guide students through: (1) Exploring the nature of knowledge; (2) Discovering connections between science and other subjects; (3) Deepening science comprehension according to their interests and abilities; and (4) Connecting science to society through the study of genetics, historic events, literature, and chemistry. Each unit includes subject matter background, a content framework, study components, teacher reflections, and sample lessons.