The ADDIE (analysis, design, development, implementation, and evaluation) model was applied to help redesign a General Chemistry course to improve student success in the course. A team of six professionals spent 18 months and over 1,000 man-hours in the redesign. The resultant course is a blend of online and face-to-face instruction that utilizes stable base groups throughout the face-to-face portion of the course. Students complete online assignments prior to class and must take a weekly online quiz each week. During face-to-face time, students answer clicker questions in groups throughout each class so class lecture has been essentially eliminated. The systematic attention to each step in ADDIE provided a well-organized process to help guide the team throughout the redesign process. The resulting design has significantly increased the average GPA for the course and significantly decreased the failure rate. (Contains 2 tables and 4 figures.)