The present study investigated if unconscious primes can be processed according to different stimulus-response (S-R) rules simultaneously. Participants performed two different S-R rules, such as judging a digit as smaller or larger than five and judging a letter as vowel or consonant. These S-R rules were administered in random order and announced by a previously presented cue. Each target stimulus was preceded by subliminal primes which afforded a different or an identical response according to either the currently irrelevant or currently relevant S-R rule. In three experiments, we consistently found priming effects according to currently irrelevant S-R rules, even when primes for the relevant and irrelevant S-R rules were presented simultaneously. Thus, unconscious stimuli have the power to activate responses according to currently required and currently not required S-R rules concurrently. The results are in line with response activation accounts of subliminal priming and suggest that at least two routes may gain access on response processes simultaneously.