Two experiments used both irrelevant speech and tones in order to assess the effect of manipulating the spatial location of irrelevant sound. Previous research in this area had produced inconclusive results (e.g., Colle, 1980). The current study demonstrated a novel finding, that sound presented to the left ear produces the greatest level of disruption. These results were explained in terms of hemispheric specialisation for processing of some supra-linguistic components in the unattended sound. Results also supported previous research by demonstrating that both forms of irrelevant sound disrupted performance on serial memory tasks (Bridges & Jones, 1996; Colle & Welsh, 1976; Jones, Alford, Bridges, Tremblay, & Macken, 1999; Jones, Miles, & Page, 1990).