In this article, I propose that at the juncture of disciplines, the mind is involved in at least 3 cognitive activities: overcoming internal monologism or monodisciplinarity, attaining provisional integration, and questioning the integration as necessarily partial. This claim is supported by interview data I collected primarily from faculty involved in the development and teaching of interdisciplinary courses in programs including the University of Pennsylvania's Center for Bioethics, Swarthmore College's Interpretation Theory, and the NEXA Program at San Francisco State University. I suggest that interdisciplinary thinking is fundamentally similar to dialogical exchanges occurring in language and in collaborative activities in which epistemological positions are bartered. Bakhtin's (1981) theory of dialogic understanding and subsequent linguistic theories of conceptual metaphor and blending serve as a constructive theoretical framework for the understanding of interdisciplinary cognition. Viewing disciplines broadly as languages, epistemologies, and collaborative practices helps uncover some underlying cognitive mechanisms that deserve further investigation.