The United States faces a looming shortage of many types of health-care professionals, including nurses, physicians, dentists, pharmacists, and allied-health and public-health workers. There may also be a shortage of faculty members in the health sciences. The results will be felt acutely within the next 10 years. Colleges and health-science programs will all be affected by the demographic, technological, and bureaucratic trends driving the pending crisis. But they can also be part of the solution. In this article, the authors call for organized action, not only within colleges, but also at the nation's highest levels to work together to avert a crisis.