Student-centered education is in the air. It is present in many reform agendas for higher education across every discipline and is shortlisted as an important goal for teaching and learning in many reports and recommendations of professional agencies and scientific societies. There is wide consensus that moving from teacher-centered to…

Student interest in artificial sweeteners can enhance the biochemistry classroom learning experience. This in class, guided-inquiry activity focuses on sucralose and fits into a 50-min biochemistry class for undergraduate science majors. Background knowledge of carbohydrate structure, function, and metabolism as well as familiarity with…

In this article, the author provides information about the Australian education landscape and discusses three articles that focus on innovative laboratory teaching programs. Each of the articles presents a novel laboratory teaching mechanism that has evolved to successfully address a perceived weakness or problem in the laboratory program. It…

Molecular cloning skills are an essential component of biological research, yet students often do not receive this training during their undergraduate studies. This can be attributed to the complexities of the cloning process, which may require many weeks of progressive design and experimentation. To address this issue, we incorporated an…

Science undergraduate courses typically cater to a mixed-learner cohort, with a diversity of motivations and skills. This diversity introduces pressure for designers of the practical laboratory curriculum. Students who are struggling with the course need a series of tasks that begin simply, and transition to more conceptually difficult material.…

The ability to write concise and accurate scientific reports is highly valued in university level science. From reflection on marking student final year reports, it was apparent that many students have had insufficient practice at writing complete "scientific paper" style reports by that time, although some do it very well. This is a previously…

Although the biochemistry education community is far from avoiding conversations about improving teaching and learning, reexamining individual and community teaching practices through the lens of the scholarship of teaching and learning (SoTL) is critical for continued growth and improvement. The contemporary vision of SoTL, which has been…

Protein engineering is a powerful tool, which correlates protein structure with specific functions, both in applied biotechnology and in basic research. Here, we present a practical teaching course for engineering the green fluorescent protein (GFP) from "Aequorea victoria" by a random mutagenesis strategy using error-prone polymerase chain…

Students benefit most from their science education when they participate fully in the process of science in the context of real-world problems. We describe a student-directed open-inquiry lab experience that has no predetermined outcomes and requires students to engage in all components of scientific inquiry from posing a question through…

The PhD graduate from a US research academic institution who has worked 5-7 years to solve a combination of laboratory and computational problems after an in-depth classroom experience is likely superbly trained in at least a subset of the life sciences and the underlying methodology and thought processes required to perform high level research.…

Podcasts are audio or video files which can be automatically downloaded to one's computer when the episodes become available, then later transferred to a portable player for listening. The technology thereby enables the user to listen to and/or watch the content anywhere at any time. Formerly popular as radio shows, podcasting was rapidly explored…

It is an extraordinary challenge to offer an undergraduate laboratory course in virology that teaches hands-on, relevant molecular biology techniques using nonpathogenic models of human virus detection. To our knowledge, there exists no inexpensive kits or reagent sets that are appropriate for demonstrating real-time PCR (RT-PCR) in an…

We have designed a laboratory curriculum using the green and red fluorescent proteins (GFP and RFP) to visualize the cloning, expression, chromatography purification, crystallization, and protease-cleavage experiments of protein science. The EGFP and DsRed monomer (mDsRed)-coding sequences were amplified by PCR and cloned into pMAL (MBP-EGFP) or…

Plant-derived phenolic compounds such as those found in red wine, tea, and certain fruit juices may protect against cardiovascular disease by detoxifying (scavenging) superoxide and other unstable reactive oxygen species. We present a laboratory exercise that can be used to assess the superoxide-scavenging capacity of beverages. Among the…

Laboratory exercises, which utilize alkaline phosphatase as a model enzyme, have been developed and used extensively in undergraduate biochemistry courses to illustrate enzyme steady-state kinetics. A bioinformatics laboratory exercise for the biochemistry laboratory, which complements the traditional alkaline phosphatase kinetics exercise, was…