This study, using data from a statewide survey (n = 332), examined teachers' practices regarding the inclusion of guest speakers to cover sexuality content. More than half of teachers (58%) included guest speakers. In multivariate analyses, teachers who taught high school, had professional preparation in health education, or who received professional development covering sexually transmitted disease (STD) or pregnancy prevention had greater odds of including guest speakers (all p < 0.05). Teachers who included guest speakers covered more sexuality topics and were more likely to cover controversial topics (p < 0.05). Findings have implications for teachers, school policies, and organizations that offer sexual health education and outreach.