"Cootie Genetics" is a hands-on, inquiry-based activity that enables students to learn the Mendelian laws of inheritance and gain an understanding of genetics principles and terminology. The activity begins with two true-breeding Cooties of the same species that exhibit five observable trait differences. Students observe the retention or…

Although the development of next-generation (NextGen) sequencing technologies has revolutionized genomic research and medicine, the incorporation of these topics into the classroom is challenging, given an implied high degree of technical complexity. We developed an easy-to-implement, interactive classroom activity investigating the similarities…

The evolution of complexity remains one of the most challenging topics in biology to teach effectively. We present a novel laboratory activity, modeled on a recent experimental breakthrough, in which students experimentally evolve simple multicellularity using single-celled yeast ("Saccharomyces cerevisiae"). By simply selecting for…

This article reviews the discovery of RNA interference, its mechanism of action and its functions, and the principles, challenges, and strategies for RNA therapeutics.

A logical question to be expected from students: "How could life develop, that is, change, evolve from simple, primitive organisms into the complex forms existing today, while at the same time there is a generally observed decline and disorganization--the second law of thermodynamics?" The explanations in biology textbooks relied upon by…

In this activity, students examine nine hominin skulls for specialized features and take measurements that will enable them to determine the relatedness of these species. They will ultimately place each specimen on a basic phylogenetic tree that also reveals the geological time frame in which each species lived. On the basis of their data, and…

Students regard evolutionary theory differently than science in general. Students' reported confidence in their ability to understand science in general (e.g., posing scientific questions, interpreting tables and graphs, and understanding the content of their biology course) significantly outweighed their confidence in understanding…

The goal of this Quick Fix is to inform biology teachers about the availability of online crossword puzzles that can be used to engage students and help them learn technical biological terms.

A collaborative effort between a junior high school and a nearby university allowed 40 eighth-grade honors students to engage in a scientific investigation within a university laboratory. These students, with their science teachers and university researchers, gathered data on egg cannibalism in a beach-spawning fish and thereby contributed to an…

An understanding of how genomics information, including information about risk for common, multifactorial disease, can be used to promote personal health (personalized medicine) is becoming increasingly important for the American public. We undertook a quantitative content analysis of commonly used high school textbooks to assess how frequently…

Various sequences for teaching genetics have been proposed. Three seventh-grade biology textbooks in Taiwan share similar key knowledge assemblages but have different knowledge arrangements. To investigate the influence of knowledge arrangements on student understanding of genetics, we compared students' reading comprehension of the three…

Evolutionary experiments are usually difficult to perform in the classroom because of the large sizes and long timescales of experiments testing evolutionary hypotheses. Computer applications give students a window to observe evolution in action, allowing them to gain comfort with the process of natural selection and facilitating inquiry…

Optimal foraging theory is a principle that is often presented in the community ecology section of biology textbooks, but also can be demonstrated in the laboratory. We introduce a lab activity that uses an interactive strategy to teach high school and/or college students about this ecological concept. The activity is ideal because it engages…

We assessed the performance of students with a self-reported conflict between their religious belief and the theory of evolution in two sections of a large introductory biology course (N = 373 students). Student performance was measured through pretest and posttest evolution essays and multiple- choice (MC) questions (evolution-related and…

In 1858, Darwin published "On the Origin of Species by Means of Natural Selection." His explanation of evolution by natural selection has become the unifying theme of biology. We have found that many students do not fully comprehend the process of evolution by natural selection. We discuss a few simple games that incorporate hands-on…