This pilot study explored the effects of Integrated Listening Systems (iLs) Focus Series on individualized parent goals for children with sensory processing impairments. A nonconcurrent multiple baseline, repeated measure across participants, single-case study design was employed (n = 7). The 40-session intervention was delivered at home and in the clinic. Individualized family goals served as the repeated measure. Exploratory analyses included the evaluation of physiological arousal. Participants showed improvement in home and education-related goals. Changes in physiologic arousal were noted in five of seven participants. Standardized scales demonstrated sensitivity to change. Thus, the iLs program may be beneficial for school- or clinic-based intervention.