This fact sheet on Down Syndrome is offered in both English and Spanish. First it provides a definition and description of this syndrome, noting its etiology in a chromosomal abnormality. Incidence figures are then given. Typical characteristics of people with Down Syndrome are listed. Commonly associated health-related problems are noted, including a lowered resistance to infection, the presence of heart defects, the condition of Atlantoaxial Instability (a misalignment of the neck vertebrae), and a tendency toward obesity. Educational and employment implications are briefly considered. These include the value of an infant development/early intervention program, the wide range of individual differences, and the need to use teaching strategies which emphasize concrete concepts rather than abstract ideas. (DB)