The major purpose of this study was to determine if significant differences in attitude change toward eight drug abuse concepts would be generated among college students when taught a drug abuse education program with the use of self-directed multi-media learning activities. The subjects' opinions and evaluation of the self-directed education program were also assessed. The study involved two classes for in-training teachers offered at Auburn University, Georgia, during the Summer quarter, 1971. An experimental class of 36 subjects was taught using self-directed multi-media learning activities while the control class of 25 subjects was taught using conventional procedures. Significant differences between means as analyzed by a Two-way Analysis of Variance Test revealed that change in attitudes occurred in the experimental group taught with the self-directed multi-media method that did not occur in the control group taught with the conventional method. An analysis of an opinion questionnaire revealed a favorable reaction by students toward the use of the self-directed drug abuse education program (Author/BL)