The purpose of the present study was to examine the relationship between bullying, victimization and a number of social-emotional variables such as trait emotional intelligence, empathy and self-efficacy in 206 elementary school 6th graders in Greece. Results indicated that boys reported significantly more direct and indirect bullying behaviors than girls, and higher victimization. Bullying was negatively correlated with overall self-efficacy and its academic component, trait emotional intelligence, empathy and its cognitive component, while victimization was negatively correlated with overall self-efficacy and its three dimensions, trait emotional intelligence, affective and cognitive empathy. Gender, trait emotional intelligence, and cognitive empathy significantly predicted bullying, whereas victimization was predicted by gender, trait emotional intelligence and affective empathy.