This study addressed utilization of technology in instruction by secondary career and technical education (CTE) teachers in seven program areas in Louisiana. A stratified random sample was utilized, with 539 teachers responding to the survey after three data collection efforts. The data were determined to be representative of all CTE teachers in the state. Most CTE teachers used self-taught approaches, workshops, conferences, and colleagues as technology training sources. CTE teachers had substantially adopted technology for use in instruction, but were not making the maximum use of technology. Teachers were experiencing minor barriers and some anxiety as they worked to incorporate technology in their instruction. As technology anxiety and perceived barriers to integrating technology in the instruction increased, technology adoption decreased. Also, technology adoption increased as technology availability increased. Business and marketing teachers adopted technology more than other CTE teachers. Technology training sources, technology available, technology adoption, technology anxiety, and barriers to technology integration were compared by CTE program area.