The basic premise of this paper is the fact that science has become a major industry: the knowledge industry. The paper throws some light on the reasons for the transformation of science from a limited, constrained and marginal craft into a major industry. It, then, presents a productivist industrial model of knowledge production, which shows its components, mechanisms, bases, rules and specificities. Accordingly, it locates the place and role of creativity and innovation in its processes. This leads to constructing a new model for the scientific method and scientific practice.