This reference guide is designed to organize and suggest acceptable practices and procedures for dealing with safety in elementary science instruction. It is intended as a reference for teachers, administrators, and other school staff in planning for science activities and in making daily safety decisions. Topics covered in the guide include: (1) responsibility; (2) animals; (3) chemicals; (4) electricity; (5) field trips; (6) first aid; (7) high risk labs; (8) lab equipment; (9) open flames; (10) plants; (11) model rockets, etc.; and (12) safety glasses. Several appendices deal with specialized considerations. (Author/RE)