Alcohol use and risk-taking behavior among 345 male adolescents from three Israeli secular (n = 168) and three religious (n = 177) high schools were studied from 2009 to 2013. Findings show the positive impact religious education and religiosity have on minimizing alcohol use, binge drinking, school underachievement, violence, weapons possession, and driving behavior. These results should be considered by school, social service, and health care personnel addressing the needs of young people, especially those in danger of school failure, drop out, and risk-taking behavior.