Single subject research is a scientific research methodology that is increasingly used in the field of special education. Therefore, understanding the unique characteristics of single subject research methodology is critical both for educators and practitioners. Certain characteristics make single subject research one of the most preferred methodologies in special education. However, the design is not without limitations. The purpose of this article, by Orhan Cakiroglu, an assistant professor at Karadeniz Technical University, Turkey, is to provide an overview of the single subject research method's critical defining features and basic designs, and discuss what types of research questions single subject research is best suited to answer by providing examples from special education literature. Additionally, the key advantages and limitations of applying single subject research to the field of special education are discussed.