This article responds to the need to synthesize theory and research in educational psychology by introducing the Thriving with Social Purpose (TSP) conceptual framework. TSP results when the four components of human motivation--goals, capability beliefs, context beliefs, and emotions--are amplified in dynamic, mutually reinforcing patterns. The centerpiece of the TSP motivational pattern is an active approach goal orientation informed by a fundamental concern for others (social purpose). This orientation is supported and strengthened by a firm belief in one's ability to make progress toward meaningful goals (personal optimism), a persistent tendency to imagine alternative pathways when progress is challenged (mindful tenacity), and intentional efforts to align emotions and circumstances in ways that will best facilitate goal progress (emotional wisdom). The TSP framework also emphasizes positive (discrepancy increasing) feedback cycles that accelerate learning and competence development, facilitate meaningful change, and promote personal and social well-being.