Over time, fewer and fewer geography scholars have the opportunity to actually engage in fieldwork. This article summarizes a field experience shared by a group of geography faculty and students who traveled through the Mississippi Delta endeavoring to study the dynamic nature of the region's blues music and culture. This endeavor entailed the utilization of a place-based approach to focus attention on the many geographical, historical, and cultural processes that have unfolded within this region over time. This approach also sheds light on the ways in which this unique region has impacted the rest of the country and the world. Socially transformative processes and issues related to the evolution of the civil rights movement and cultural diffusion are given specific attention.