This guide provides background information on the development and implementation of thematic units that focus on a hands-on approach, process orientation, integrated curriculum, cooperative learning, and critical thinking. Topics of the thematic units and mini-units include wild animals, dinosaurs, rainforests, the human body, earth science, oceans, simple machines, inventions, space science, and weather. An outline for a professional development activity focusing on creative science teaching is also provided. Appendices contain information on teacher resources, science periodicals for students, and Web sites. (DDR)