The impact of Physics laboratory on students was carried out among senior secondary school students offering Physics in Ethiope West Local Government Area of Delta State using descriptive survey. Five public schools were random-even samplying technique was adopted for precision. Fifty questionnaires were distributed to students in each school, making it a total of 250 students in all schools and retrieved immediately to avoid alteration of information. Percentage analysis was to evaluate the collected data. The findings revealed that physics laboratory helps in the teaching of physics students in senior secondary schools, in Ethiope West L.G.A. of Delta State, because 80.4% of the respondents agreed to the statement while 19.6% disagreed. Also, 87.2% accepted that physics practical improve learning that stimulate positive impact while 12.8% disagreed. 92.2%, 75.9% and 88.3% agreed while 7.8%, 24.1% and 11.7% disagreed with the statements; there is a significant relationship between students and teachers during experimental classes, physics laboratory helps to inculcate scientific reasoning among physics students and physics laboratory enhances students' performance in physics in senior secondary schools in Ethiope West L.G.A. of Delta State respectively.