Although there have been claims of significant therapeutic benefits arising from the use of deep touch pressure techniques with children with autistic spectrum disorders, to date there have been few empirical investigations of its use with adults with autistic spectrum disorders and anxiety in clinical practice. This paper reports on the systematic use of deep touch pressure within a structured programme for a man with autism who was presenting with severe challenging behaviour. The programme led to significant reductions in the use of both physical restraint and medication, as well as appropriate physiological changes, with a parallel increase in the person's quality of life. The implications of this approach are discussed with regard to both theory and practice with the aim of increasing the provision of more appropriate forms of support for people who present with challenging behaviour.