In the late 1990s the Phillips neighborhood in Minneapolis was dangerous and crumbling, prompting "The New York Times" to dub the city "Murderapolis." As Minneapolis' largest neighborhood in size and population, and Minnesota's most culturally diverse community, the Phillips neighborhood became a negative symbol of urban blight in the city's core. With leadership from local business executives and creative private and public fundraising, a partnership was created to address long-term quality-of-life issues revolving around jobs, housing, and education. This paper describes the Health Careers Institute (HCI), a partnership whose members include the Minneapolis Community and Technical College, Abbott Northwestern Hospital, Children's Hospitals & Clinics, and Hennepin County Medical Center. Health care officials have stated that HCI is the nation's largest and most successful hospital-based jobs program, with many graduates coming directly from the economically challenged Phillips neighborhood. This partnership has proved to be a powerful economic tool, and has provided economic stability to the Phillips neighborhood through a market-driven approach to workforce training and education.