Teacher education in India, including that offered by the open distance learning (ODL) system to thousands every year, imparts mainly pedagogic knowledge, although the need for integrated teacher education programmes has been underscored. As the Indira Gandhi National Open University (IGNOU), an ODL institution, will develop an integrated Bachelor of Education programme for secondary-level teachers, a model based on the Technological Pedagogical Content Knowledge (TPACK) framework has been proposed for developing and implementing it. The model takes cognisance of the systemic challenges to TPACK-based teacher education, but it does not envision radical changes in IGNOU's teacher education framework for addressing these challenges. It includes propositions with theoretical underpinnings for redesigning the major components of the framework while retaining its basic structure. The model has been described in terms of its rationale, its structure and the way it envisages the progress of teacher trainees from a phase of learning with the help of self-learning material designed for imparting integrated theoretical knowledge to one whereby they apply such knowledge in simulated situations, and finally moving on to a phase of situated learning during internship.