After birth, newborns and their caregivers are seen routinely and frequently in pediatric primary care settings. The close succession of visits in the first few months of life puts pediatric primary care professionals in a unique position to enhance infant mental health by developing strong relationships with caregivers, supporting babies and their families, and providing critical information about development and well-being. This article describes Project CLIMB, an integrated mental health program located within a busy pediatric primary care training clinic, and how it incorporates infant mental health principles into direct services and educational offerings.