This paper is the eighth in the Association of Governing Boards of Universities and Colleges (AGB) biennial series summarizing federal and state public-policy issues affecting higher education. This document's list of top public-policy issues comprises a daunting inventory for boards and chief executives to consider. Security demands of the post-9/11 world will continue to require colleges and universities to function with more-intrusive federal restrictions. The following public policy issues are discussed in this document: (1) Homeland Security; (2) Scientific Research; (3) The Price of Tuition; (4) Participation of Low-Income Students; (5) Diminishing State Capacity for Setting Higher Education Policy; (6) The Culture Wars; (7) Economic and Workforce Development; (8) Accountability to the Public; (9) Ownership of Intellectual Property; and (10) Aftereffects of Sarbanes-Oxley.