ERIC Number: EJ1050712
Record Type: Journal
Publication Date: 2015-Jan
Pages: 4
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0021-9584
EISSN: N/A
Recruiting the Students to Fight Cancer: Total Synthesis of Goniothalamin
Nahra, Fady; Riant, Olivier
Journal of Chemical Education, v92 n1 p179-182 Jan 2015
A modified total synthesis of (S)-goniothalamin is described for an advanced course in organic chemistry. This experiment gives students an opportunity to handle organometallic reagents and perform an enzymatic kinetic resolution and a metathesis reaction, all in the same synthesis. Furthermore, students learn flame-drying techniques for the manipulation of air-sensitive materials and high-performance liquid chromatography handling and analysis, thus strengthening their experimental knowledge.
Descriptors: Cancer, Synthesis, Organic Chemistry, Science Experiments, Biochemistry, Hands on Science, Undergraduate Students, Science Materials, Science Education, Teaching Methods, Laboratory Experiments
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A