This article reports on a study which investigated the impact of globalization on scientific research in Nigeria. The research data were collected using a questionnaire survey which was administered to academics in science-based disciplines in four Nigerian universities: University of Calabar, University of Uyo, University of Lagos and University of Ibadan. The results of the study show that ease of scientific communication, an increased access to current scientific books/journals and improvements in the quality of research were considered the main effects of globalization on scientific research in Nigeria. The findings of the study also show that the major factors considered to impede globalization of science in the country were frequent power cuts, a poor maintenance culture of ICT infrastructures/facilities, and an inadequate knowledge/awareness of the potential and capabilities of ICT by Nigerian scientists. Relevant recommendations based on these findings are made. (Contains 6 tables.)