The neuroscience revolution has brought a set of difficult, at times uncomfortable, changes in university-based research psychology. The technologies that allow scholars to probe the structures and functions of the human brain are also causing profound alterations in the structures and functions of psychology departments: curricula, hiring patterns, budgets, and tenure-and-promotion expectations are all shifting. This article discusses how young discipline of neuroscience has changed the way academic psychology departments hire, promote, and do research. Five young scholars with extensive training in neuroscience are presented.