School nurses provide an important role in the continuity of health care especially for adolescents who are at high risk for significant health concerns. The purpose of this study was to assess adolescents' health information needs and identify their preferences for accessing health information. Using an inductive qualitative research design, 11 focus groups were conducted with a convenience sample of 101 junior high and high school students in suburban northeastern Illinois. The students identified a variety of health concerns and emphasized the need for accessible, high-quality, and personally relevant information. Most students favored taking an active role in learning about their health. They preferred to directly access information from qualified individuals within comfortable, trusting, and respectful relationships or to indirectly retrieve information from reliable resources. Finally, students emphasized the need for privacy and a variety of learning options depending on the specific health topic. (Contains 3 tables.)