Objective: The authors examined differences in exercise motivation between age, sex, and race for college students. Participants: Students from 156 sections of physical activity classes at a midsize university were recruited (n = 2,199; 1,081 men, 1,118 women) in 2005-2006 and volunteered to complete the Exercise Motivation Inventory. Methods: Quantitative, cross-sectional descriptive research design was employed. Results: Significant differences were found in 3 of 14 exercise motivational subscales by age (affiliation, health pressures, and ill health avoidance) (p less than 0.05). Males were motivated by intrinsic factors (strength, competition, and challenge) (p less than 0.05) and females by extrinsic factors (ie, weight management and appearance) (p less than 0.05); only 2 subscales proved not to be significant by sex. Race differences provided 8 significant differences by exercise motivations (p less than 0.05). Conclusions: Significant differences for exercise motivations in college-aged population by demographics were documented. Understanding these differences is important for college health professionals for programming strategies and promoting physical activity. (Contains 5 tables.)