The Virtual Museum of Minerals and Molecules (VMMM) is a web-based resource presenting interactive, 3-D, research-grade molecular models of more than 150 minerals and molecules of interest to chemical, earth, plant, and environmental sciences. User interactivity with the 3-D display allows models to be rotated, zoomed, and specific regions of interest to be highlighted. The VMMM has been online since 1998 and currently serves 100,000 to 250,000 unique visitors annually from two mirror sites. In concept, it is a blend of a static bricks-and-mortar physical museum with wings, galleries, and displays with dynamic 3-D first-person video games. This museum is virtual not only in the sense that it exists in electronic format but also because the molecular size of the objects makes them colorless and imperceptibly small. To date, molecular visualization has been enabled in browsers using a proprietary third-party plug-in; compatibility with diverse platforms and browsers has been reduced over past years and recourse to open-source, molecular visualization Java applets may be required to avoid technological obsolescence. (Contains 3 figures.)