This article examines the topic of Dialectical Behavior Therapy (DBT) applied in college counseling centers. Trends in mental health issues on college campuses are briefly reviewed in support of the increased need for evidence-based treatment of severe mental health issues. The article next presents an overview of the standard DBT model and reviews research regarding DBT in college counseling centers, focusing on clinical outcomes and adaptations made for the college counseling setting. Finally, there is a discussion of implications for practice, barriers to implementation and outcome measurement, and areas for future research.