The purpose of this article is to suggest a research-based systemic plan for educational researchers, practitioners, and policymakers involved in the change process to implement successful technology integration in the context of teacher education. This article provides a background about reform efforts in science education in the United States in recent years. This article also addresses technology tools that are responsive to reform efforts in the elementary science education and indicates the challenges of modifying elementary preservice teacher education to meet technology reform needs. The technology integration change process takes time and efforts; not all change can be sustained. Thus, a systemic plan that considers three major components, including people, process activities, and systems, to ensure successful technology integration is suggested.