This study examined the relationships among motivational orientations based on self-determination theory (Ryan & Deci, 2000b) and burnout among undergraduate college students. A sample of 191 university students was administered the "Academic Motivation Scale" (Vallerand et al., 1992) and the "Maslach Burnout Inventory-Student Survey" (Schaufeli, Martinez, Pinto, Salanova & Bakker, 2002). The results suggest that intrinsic motivation to attend college was associated with lower levels of burnout, while amotivation and external regulation were associated with higher levels of burnout. Identified regulation was negatively related to one dimension of burnout (i.e., professional efficacy). The results and their implications for practice and future research are discussed in the context of self-determination theory. (Contains 2 tables.)