Two experiments combined a spatial cueing manipulation (valid vs. invalid spatial cues) with a stimulus repetition manipulation (repeated vs. nonrepeated) in order to assess the hypothesis that familiar items need less spatial attention than less familiar ones. The magnitude of the effect of cueing on reading aloud time for items that were repeated throughout the experiment was smaller than the magnitude of the cueing effect for items that were not repeated within the experiment. These results are consistent with the idea that familiarity within an experiment modulates the spatial attentional demands of word processing. Implications for understanding spatial attention's role in reading are discussed. (Contains 3 figures and 3 footnotes.)