The pressure on higher education to become more innovative and effective with respect to its teaching and learning (T&L) mission is unceasing. Institutions are challenged to rethink how they perform this core mission. The campus IT organization, always of strategic importance, can become a key partner and facilitator in that process. Its opportunities lie in becoming actively engaged in the T&L mission, not just as a supporting player but also as a proactive change agent, working to enable the institution to construct a new vision for T&L and to move toward its realization. To do so will require a rethinking of the roles of the chief information officer (CIO) and the academic technologist, as well as a new vision for the campus academic technology infrastructure.