Objectives: Advances in electronics, the Internet and telecommunication have pushed the field of health care to embrace information technology (IT). However, the purposeful use of technology is relatively new to the field of health promotion. The primary objective of this paper is to review various applications of health IT, with a focus on its use in health promotion and its evolving impact on the healthcare system in the USA. It also emphasises on the potential benefits of introducing different applications of health IT in health care and health education. Methods: A detailed review and synthesis of recent literature in the area of health IT was conducted to reflect and describe the recent trends related to health promotion influenced by IT in the USA. Results: This review reveals that despite initial reluctance, health providers and patients are accepting and even crediting health IT for providing patients with resources to educate themselves on their health status and actively participate in their health care by enabling them easy access to health information. Conclusion: Health-related IT can facilitate a paradigm shift from a system-centred disease prevention model of care to a more patient-centred health promotion approach. Furthermore, like most other changes in health care, health IT is facing its share of challenges, yet evolving to be one of the fastest growing trends in the US healthcare system.