The research studies the quality of life (QOL) of 127 men and women diagnosed as having a borderline IQ and ADHD living in two major residential programs of the Sharon region in central Israel in respect to their personal, disability, and social ecological variables. Core findings indicate that men and women differ significantly according to their educational background. Among those who studied in a regular educational environment, the main predictor of men's QOL is their monthly income, whereas the main predictor for women is their level of attention deficit symptoms. The only predictor of QOL among men who studied in a special education program is the quality of contact with their mothers, whereas no significant predictor is observed among women. (Contains 5 tables.)