In science, inquiry is used as students explore important and interesting questions concerning the world around them. In mathematics, one contemporary inquiry approach is to create models that describe real phenomena. Creating mathematical models using spreadsheets can help students learn at deep levels in both science and mathematics, and give teachers an excellent opportunity to integrate these two disciplines. The project described in this article involves a melding of mathematical and scientific processes. The two scientific concepts explored involve physics, specifically Hooke's law and Newton's laws of heating and cooling, though the modeling described can be used in many places in the science curriculum. The mathematics, which is appropriate for students at the introductory algebra level or higher, includes regression analysis, the parameters in a model, and the errors that inevitably occur.