Native American and First Nations (herein collectively referred to as Indigenous) women college students are faced with the challenge of balancing their cultural imperatives and the demands of the dominant Western culture in family, school, and work/employment roles. In order to explore these women's experiences and perspectives, this study analyzed unstructured qualitative interviews of 11 Native American and 9 First Nations female college students. The themes that resulted from the hermeneutic analysis were (a) honoring Indigenous culture and community, (b) living in two worlds, (c) pursuing individual fulfillment and goals, and (d) acknowledging the importance and influence of family.