Entrepreneurship is perceived to be a key to revitalizing the economies of American Indian communities. Gonzaga University offers an MBA specifically designed to prepare tribal college instructors to teach entrepreneurship. Beginning with the relevant background on the need for and benefit of indigenous management education, this article describes the elements of this unique program such as the cohort system, on-line and on-campus courses, and culturally appropriate curriculum changes. The program is analyzed through a qualitative examination of an alumni survey. The survey reveals that the foremost challenge for the program is the integration of indigenous cultural values and management practices with mainstream business curricula. The most prominent success factor the survey reveals is the fit between the program's goals and the mission of the Jesuit institution in which the program resides. Finally, the survey results provide some insight into the impact the program is having on indigenous communities. (Contains 1 note, 1 table, and 2 figures.)