Using survey data from 1,036 participants, which included 4 immigrant groups, we examined the factors that influence immigrants' experiences as they interact with nonimmigrant Americans. Logistic and multinomial regression results indicate that non-European immigrants were more likely to report negative experiences with Americans. The odds of reporting negative interactions were lower for African than for Hispanic immigrants. Immigrants who have lived in the United States for 10 years or longer and immigrants who have been involved in community activities were more likely to report negative interactions. Immigrants with employment, perception of lack of cultural understanding, and limited English proficiency also reported positive interaction. The study reinforces the need for social workers to facilitate intergroup relations among diverse populations. (Contains 3 tables.)