The booklet describes the Association for Retarded Citizens' (ARC's) goal of coordinating efforts to seek a cure for mental retardation. Cures are defined as any intervention that would significantly increase intellectual functioning and adaptive behavior beyond the upper level of retardation. It is explained that because of the variety of causes for retardation, the search must involve multiple cures. The notion of prevention as one type of cure is addressed. Recent advances in scientific research (on such aspects as enzymes, possible regeneration of nerve cells, and addition of brain hormones) are noted. A conference on current and future research is summarized, and developments reported. The booklet concludes with a series of questions and answers about ARC's position on the issue. (CL)