The purpose of this study was to examine the connections between national culture and student achievement. Using Hofstede's six cultural dimensions and the two dimensions from the World Values survey, we conducted multiple regressions to determine the most significant predictors of student achievement as measured by the 2009 Program for International Student Assessment in reading, mathematics, and science. Our analyses found that the most significant predictors of student achievement on all three student outcome included the following cultural dimensions based on two different frameworks: (1) a culture's focus on fostering long-term orientation to include emphasis on perseverance to achieve future-oriented results and (2) a culture's focus on secular-rational values vs. traditional values. In addition, findings indicate that when mapped geographically, similar patterns emerge among the two cultural dimensions.