It is a common assumption that mothers who have had previous births would participate less fully and have poorer outcomes from early home visitation programs than would first-time mothers. The authors conducted a qualitative and quantitative study to test that assumption by measuring three aspects of participation: time in the program, the number of home visits, and the intensity of services. The study also assessed three outcomes: immunizations, the home environment, and subsequent births. Data from more than 4,000 participants at Healthy Families Virginia sites indicate that mothers who had had previous births participated and benefitted similarly to first-time mothers. These findings suggest a need for future research to better understand the conditions under which home visiting works, and they have policy implications concerning the value of universal home visitation.