Healthy school environments are essential to ensure the best setting for learning. When school environments are unhealthy, students and staff may be exposed to harmful pollutants and chemicals that can cause their health, attendance, and scholastic performance to suffer. Among the factors that can affect the environmental quality of school indoor environments are school siting, building materials and operation, and maintenance practices including management of moisture and mold pests, lab and other chemicals, and cleaning products. One of the maintenance practices that should be considered by all schools is "green cleaning." While there is no standardized definition for green cleaning, health and environment experts recommend safe and environmentally friendly cleaning practices to provide effective cleaning processes that protect the environment and prevent toxic exposures of students and staff. This article documents--through both scientific evidence and anecdotal reports--the considerable benefits of introducing green cleaning practices in schools, with an emphasis on human health and cost savings. (Contains 1 table and 28 endnotes.)