Background: Community collaboratives provide a means to build local capacity, reduce service fragmentation and duplication, maximize efficiency, and create synergies for "systems change". But what are the collaborative practices that aging services providers and other stakeholders employ for "system change" and "impact" in evidence-based programming for older adults? Purpose: The aim of this study was to learn how aging and health collaborations created strategic partnerships to foster multisector "systems change" and pursue long-term goals and near-term activities to sustain and expand evidence-based health programming. Methods: Via a multiphase process, we identified eight geographically diverse, exemplar agencies that serve as the coordinators for various community collaborations. Using an interview protocol culled from the literature, we conducted on-site, in-depth interviews with leadership and partners. Results: Four creative strategies emerged across sites as contributing to the growth and sustainability of evidence-based health programming including engagement of nontraditional partners, development of new relationships with health care, building of innovative systems of structures and tools, and systematically working with vulnerable populations. Opportunities for future initiatives include enhancing linkages with health care, advocating for the value of evidence-based programming, supporting local program development and adaptation, and developing marketing strategies and business models. Conclusion: These eight organizations are leveraging their historic strengths and newly acquired expertise to extend health programming beyond established partners and funding silos. The four strategies and specific activities reflected in their work have laid a solid foundation for expanding and embedding future initiatives and positively impacting the health of older adults. [This article is part of an open access supplement "Fostering Engagement and Independence: Opportunities and Challenges for an Aging Society," published in SOPHE's Health Education & Behavior. This supplement was supported by funding provided by the Centers for Disease Control and Prevention's (CDC) National Center for Chronic Disease Prevention and Health Promotion, Healthy Aging Program (Cooperative Agreement #U38HM 000454) via the Association of State and Territorial Health Officials, and from a grant provided by the Retirement Research Foundation.]