This report presents an approach to welfare reform using the welfare-to-work programs possible under the Job Opportunities and Basic Skills Training (JOBS) portion of the Family Support Act. The document describes how state and local governments can design and implement two-generation interventions that combine services to help parents achieve self-sufficiency with supports for children's healthy development and school success. Part I describes the following six basic elements of a two-generation intervention and options for program design: (1) assessment of child and family needs; (2) high quality child care and early childhood education; (3) services that strengthen parenting; (4) preventive health services for children and parents; (5) self-sufficiency services leading to parental employment; and (6) case management. Part II profiles the following eight programs that currently deliver two-generation services under the Family Support Act: (1) Kentucky JOBS Program; (2) Hawaii JOBS Program; (3) Denver (Colorado) Family Opportunity Program; (4) Baltimore (Maryland) LOCATE Service; (5) Child Care Planning for JOBS in the Illinois Department of Public Aid; (6) Philadelphia (Pennsylvania) JOBS' Collaboration with Head Start; (7) Tampa (Florida) JOBS Programs: Orientations on Preventive Health Care; and (8) Portland (Oregon) Teen Parent Program. Contact person information is included. Part III contains information about 18 organizations as resources that may be useful in ongoing work to create two-generation self-sufficiency programs including organizations that are providing technical assistance and projects that are tracking and disseminating information about JOBS and related programs. Included are 48 endnotes and an appendix containing a background and synopsis of the JOBS program. (JB)